currently for me:
Wolf and Spice (or Spice and Wolf. whichever). A little slow paced, but interesting characters.
Ghost Hound. Uhm, wow. Production I.G. scores again. Seemed a bit odd of a concept for the first couple of episodes, but the main plot seems to have gotten rolling now. Gorgeous artwork, especially if you grab the 1080p fansubs from Ureshii. This is one would be good to show off that shiny new HDTV you got at the post Super Bowl sale.
Moonlight Mile/ Moonlight Mile Touchdown. Some gratuitous fanservice that really doesn't serve any purpose in the first episode, but a damn nice near future SF story.